Dayaram PharmaChem is supplying, distributing and dealing in Indianstates are Tamil Nadu, Telangana, Gujarat, Maharashtra, Punjab, West Bengal,Karnataka, Andhra Pradesh, Delhi, Rajasthan, Haryana, Madhya Pradesh, UttarPradesh, Uttarakhand, Chhattisgarh, Assam, Orissa, Bihar, Chandigarh, Goa,Jharkhand, Jammu & Kashmir, Kerala, Manipur, Meghalaya, Mizoram, Sikkim,Tripura with all require documents.
IUPAC NAME: 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-(pyrimidin-2-yl)pyrimidin-4-yl] benzene-1-sulfonamide
MOLAR MASS: 551.614 gÃÂ·molÃ¢ÂÂ1
Drug Interaction: Thisdetails does not contain all possible drug interactions. The medicines you usemake list and share it to doctor or pharmacist. Without doctor approval donÃ¢ÂÂtchange, stop or start to use any drug. Drug interaction may change according tomedication work or increase risk for serious adverse effects.
The hormonal birth control such as pills, patch orrings Bosentan may decrease. While using this medicine talk to the doctor aboutusing a reliable birth control method. The sign of birth control is not workingwell is new spotting or break through bleeding.
Dosage: Usuallytake this medicine twice daily with food or without food or as directed bypharmacist. Dosage of this drug is depend on medical condition, treatmentresponse and body weight. The experts usually start with low doses of thismedicine and then increase in dose in some weeks or days. Use this medicineregularly to get more benefit from it. Take it same time daily to helpremember. Without consult with expert do not stop, change or start doses ofthis medicine. Doses may need to decrease gradually. Women who pregnant orbecome pregnant should not handle more medicines. DonÃ¢ÂÂt crush this medicinebecause doing so will increase exposures to the dust. Talk to the doctor if itis continue condition persists or worsens.
Side Issues: Bosentanmay cause side effects like headache, sluicing, pain in joints, nose runny orthroat pain and cold symptoms. If any effects occur tell to your doctor orexpert. He or She has judged you that benefit to you. Get medical help rightaway if notice any serious symptoms like fever, rashes, swelling on face,throat, tongue, dizziness, breathing problem.
Many people taking this medicine donÃ¢ÂÂt have anyserious side effects. This medicine may decrease sperm production in men. Talkto doctor for more details. Very serious adverse effect or allergic reactionfrom this drug is rare.
Precaution: Bosentancan cause serious side effects like liver damage, serious birth defects. Only ablood test can show if you have liver problem. Before take Bosentan must havetest to check liver functions each month after that. The doctor or expert orderfor these tests because blood tests are important that can doctor or healthcareprovider adjust or change treatment before there is permanent damage.
While taking Bosentan if you have any of thesesymptoms as gagging, vomiting, fever, unusual weakness, abdominal pain,jaundice (yellow fever) kindly share to your doctor. Bosentan cause serious birthdefects if used in pregnancy. Must donÃ¢ÂÂt use this drug when pregnant. Seriousbirth defects from Bosentan can happen early in pregnancy. During Bosentantreatment women who have able to get pregnant must have a negative report testbefore starting this medication. Discuss with health provider or gynecologistto suggest about how to prevent pregnancy. DonÃ¢ÂÂt have unprotected sex. Talkwith doctor if miss menstrual period or think you may be pregnant.
This drug make dizzy. DonÃ¢ÂÂt drive, operate machinery,or do any activity that requires alertness until you can perform theseactivities safely. Avoid alcohol, since they can increase the effects ofdizziness and also increase the risk of liver issues. This medicine may harm anunborn baby. It is known whether this drug passes into breast milk. Whiletaking this medicine is not suggested Because of the possible risk to the baby,breast feeding.
Overdose: Themost common side effect was head pain or mild to moderate intensity. It hasbeen given as a single dose up to 2400 mg in normal volunteers, up to 2000mg/day for 2 months in patients, without any major clinical result. Gentledecrease in blood pressure and increase in heart rate were observed. But noserious side reaction. After overdose of 10,000 mg of this drug symptoms arelike nausea, dizziness, hypertension, sweating, and vision blurred. And afterthis recovering within 24 hours with blood pressure support. This is unlikelyto be effectively removed by dialysis due to the high molecular weight and extensiveplasma protein binding.
Contact emergency poison control center or emergencyroom immediately if overdose doubt. Overdose symptoms like headache, dizzy,nausea, vomiting.
Notes: Donot share Bosentan to others without advice from doctor or expert. Before youstart this medication medical tests should be done. Consult your expert formore information.
Medicine Storage: Awayfrom light and moisture. Store at room temperature. DonÃ¢ÂÂt store at bathroom.Keep all medicine away from children & pets. To do so unless instructed,donÃ¢ÂÂt discharge medicine into a drain and donÃ¢ÂÂt flush medicines down thetoilet. Properly discard this product when it is expired or no longer needed. Consultpharmacist or local waste disposal company.
Bosentan found inmarket as follow:
Bosentan 62.5 MG
Bosentan 125 MG