BOSENTAN

BOSENTAN

Product Details:

  • Assay Not less than 98% w/w and not more than 102% w/w
  • Heavy Metal (%) Not more than 20 ppm
  • HS Code 29420090
  • Storage Room Temperature
  • Molecular Weight 551.614 Grams (g)
  • Smell No Smell
  • Taste Other
  • Supply Ability : 10 Kilograms Per Day
120000.00 - 145000.00 INR/Kilograms
X

Price And Quantity

  • 120000.00 - 145000.00 INR/Kilograms
  • 10 Kilograms

Product Specifications

  • C27H29N5O6S
  • Other
  • 99
  • Medicine Grade
  • Powder
  • No Smell
  • 551.614 Grams (g)
  • Room Temperature
  • Other
  • White to Pale-yellow color powder
  • 29420090
  • Bosentan take regularly to get most benefit from it. Before start using this medicine ask doctor or pharmacist. Take this medicine by mouth with food or without food. This medicine use to treat lungs (PAH) high blood pressure. When increased level of a certain natural substance this medicine block the effects of endothelin-1, which helps lower blood pressure in the lungs & slow the worsening of symptoms from this disease, and improve the ability of exercise. Bosentan can harm to foetuses and pregnant women must not take it. It may render hormonal contraceptives ineffective so other forms of birth control must be used. It is used to treat who moderate pulmonary artery hypertension and reduce the number of digital ulcers. Due to increased risk of increased liver impulse & liver destruction when these two agents are taken together, Bosentan is also contraindicated in patients taking glyburide.
  • 147536-97-8
  • Not more than 20 ppm
  • Not less than 98% w/w and not more than 102% w/w
  • 99

Trade Information

  • NhavaSheva By Sea and Sahar Airport By Air
  • Paypal, Western Union, Telegraphic Transfer (T/T), Letter of Credit at Sight (Sight L/C), Letter of Credit (L/C), Delivery Point (DP), Days after Acceptance (DA), Cheque, Cash in Advance (CID), Cash Advance (CA), Cash on Delivery (COD), Cash Against Delivery (CAD)
  • 10 Kilograms Per Day
  • 7 Days
  • Yes
  • Contact us for information regarding our sample policy
  • HDPE drum with inner LPDE liners
  • Africa, Middle East, Western Europe, Eastern Europe, South America, North America, Central America, Australia, Asia
  • West Bengal, Uttarakhand, Uttar Pradesh, Tripura, Telangana, Tamil Nadu, Sikkim, Rajasthan, Pondicherry, Punjab, Odisha, Nagaland, Manipur, Meghalaya, Mizoram, Maharashtra, Madhya Pradesh, Lakshadweep, Kerala, Karnataka, Jharkhand, Jammu and Kashmir, Himachal Pradesh, Haryana, Goa, Gujarat, Daman and Diu, Dadra and Nagar Haveli, Delhi, Chandigarh, Chhattisgarh, Bihar, Arunachal Pradesh, Assam, Andhra Pradesh, Andaman and Nicobar Islands, West India, East India, North India, Central India, South India, All India

Product Description

Dayaram PharmaChem is supplying, distributing and dealing in Indianstates are Tamil Nadu, Telangana, Gujarat, Maharashtra, Punjab, West Bengal,Karnataka, Andhra Pradesh, Delhi, Rajasthan, Haryana, Madhya Pradesh, UttarPradesh, Uttarakhand, Chhattisgarh, Assam, Orissa, Bihar, Chandigarh, Goa,Jharkhand, Jammu & Kashmir, Kerala, Manipur, Meghalaya, Mizoram, Sikkim,Tripura with all require documents.      

CAS NO:147536-97-8

FORMULA: C27H29N5O6S

IUPAC NAME: 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-(pyrimidin-2-yl)pyrimidin-4-yl] benzene-1-sulfonamide

MOLAR MASS: 551.614 g·mol−1

Drug Interaction: Thisdetails does not contain all possible drug interactions. The medicines you usemake list and share it to doctor or pharmacist. Without doctor approval don’tchange, stop or start to use any drug. Drug interaction may change according tomedication work or increase risk for serious adverse effects.

The hormonal birth control such as pills, patch orrings Bosentan may decrease. While using this medicine talk to the doctor aboutusing a reliable birth control method. The sign of birth control is not workingwell is new spotting or break through bleeding.

Dosage: Usuallytake this medicine twice daily with food or without food or as directed bypharmacist. Dosage of this drug is depend on medical condition, treatmentresponse and body weight. The experts usually start with low doses of thismedicine and then increase in dose in some weeks or days. Use this medicineregularly to get more benefit from it. Take it same time daily to helpremember. Without consult with expert do not stop, change or start doses ofthis medicine. Doses may need to decrease gradually. Women who pregnant orbecome pregnant should not handle more medicines. Don’t crush this medicinebecause doing so will increase exposures to the dust. Talk to the doctor if itis continue condition persists or worsens.        

Side Issues: Bosentanmay cause side effects like headache, sluicing, pain in joints, nose runny orthroat pain and cold symptoms. If any effects occur tell to your doctor orexpert. He or She has judged you that benefit to you. Get medical help rightaway if notice any serious symptoms like fever, rashes, swelling on face,throat, tongue, dizziness, breathing problem. 

Many people taking this medicine don’t have anyserious side effects. This medicine may decrease sperm production in men. Talkto doctor for more details. Very serious adverse effect or allergic reactionfrom this drug is rare.    

Precaution: Bosentancan cause serious side effects like liver damage, serious birth defects. Only ablood test can show if you have liver problem. Before take Bosentan must havetest to check liver functions each month after that. The doctor or expert orderfor these tests because blood tests are important that can doctor or healthcareprovider adjust or change treatment before there is permanent damage.

While taking Bosentan if you have any of thesesymptoms as gagging, vomiting, fever, unusual weakness, abdominal pain,jaundice (yellow fever) kindly share to your doctor. Bosentan cause serious birthdefects if used in pregnancy. Must don’t use this drug when pregnant. Seriousbirth defects from Bosentan can happen early in pregnancy. During Bosentantreatment women who have able to get pregnant must have a negative report testbefore starting this medication. Discuss with health provider or gynecologistto suggest about how to prevent pregnancy. Don’t have unprotected sex. Talkwith doctor if miss menstrual period or think you may be pregnant.

This drug make dizzy. Don’t drive, operate machinery,or do any activity that requires alertness until you can perform theseactivities safely. Avoid alcohol, since they can increase the effects ofdizziness and also increase the risk of liver issues. This medicine may harm anunborn baby. It is known whether this drug passes into breast milk. Whiletaking this medicine is not suggested Because of the possible risk to the baby,breast feeding.    

Overdose: Themost common side effect was head pain or mild to moderate intensity. It hasbeen given as a single dose up to 2400 mg in normal volunteers, up to 2000mg/day for 2 months in patients, without any major clinical result. Gentledecrease in blood pressure and increase in heart rate were observed. But noserious side reaction. After overdose of 10,000 mg of this drug symptoms arelike nausea, dizziness, hypertension, sweating, and vision blurred. And afterthis recovering within 24 hours with blood pressure support. This is unlikelyto be effectively removed by dialysis due to the high molecular weight and extensiveplasma protein binding.       

Contact emergency poison control center or emergencyroom immediately if overdose doubt. Overdose symptoms like headache, dizzy,nausea, vomiting.

Notes: Donot share Bosentan to others without advice from doctor or expert. Before youstart this medication medical tests should be done. Consult your expert formore information.

Medicine Storage: Awayfrom light and moisture. Store at room temperature. Don’t store at bathroom.Keep all medicine away from children & pets. To do so unless instructed,don’t discharge medicine into a drain and don’t flush medicines down thetoilet. Properly discard this product when it is expired or no longer needed. Consultpharmacist or local waste disposal company.   

References:

https://www.verywellhealth.com/

https://www.webmd.com/

https://examine.com/

https://www.practo.com/

https://go.drugbank.com/

https://pharmeasy.in/

https://www.1mg.com/

https://www.medplusmart.com/

https://www.healthline.com/

https://www.medicalnewstoday.com/

https://www.ndrugs.com/

https://www.drugs.com/

https://www.medindia.net/

https://www.zauba.com/

Bosentan found inmarket as follow:

Bosentan 62.5 MG

Bosentan 125 MG

Bosentan hydrate

Bosentan label

Bosentan msds

Bosentan synthesis

Bosentan tab


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